The MAKTREK® delivery system is the reason I chose this. Most probiotics I'd tried clearly weren't working — 40 billion CFU means nothing if the bacteria die in your stomach. Six weeks in and the difference in regularity and comfort is real and consistent.
Gut Health · Immune Support
Probiotic
Four-strain probiotic with guaranteed intestinal delivery. MAKTREK® technology protects live cultures through stomach acid — so the full complement of bacteria reaches the intestine where they can establish and work.
Four-strain probiotic with guaranteed intestinal delivery. MAKTREK® technology protects live cultures through stomach acid — so the full complement of bacteria reaches the intestine where they can establish and work.
- 40 Billion CFU, 4 strains — La-14, Bl-04, Lp-115 and Lpc-37, each with a distinct clinical role
- MAKTREK® Bi-Pass Technology — marine polysaccharide matrix protects live cultures through stomach acid
- Marine polysaccharide + FOS prebiotics — supports colonisation and short-chain fatty acid production
★★★★★
4.8 · 16 verified reviews
Ships within 1 business day · 2–4 day express delivery
↑52%
more gut microbial diversity
Diverse gut microbiome from four clinical strains
↓35%
less bloating by week 3
Reduces bloating and post-meal digestive discomfort
↓27%
lower risk of respiratory illness
Strengthens immune defence through the gut-immune axis
↑3×
more beneficial bacteria established
Supports colonisation with FOS and marine polysaccharide prebiotics
↓61%
stronger gut lining
Reduces intestinal permeability and leaky gut symptoms
↑94%
bacteria survive to reach the gut
MAKTREK® Bi-Pass ensures the full 40B CFU reaches the intestine
Probiotic
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The Experience
What You'll Feel
Week 1
MAKTREK® Delivery
The marine polysaccharide matrix begins protecting the 40 Billion CFU through stomach acid. Strains arrive intact in the intestine and initiate colonisation — the foundation of everything that follows.
Week 2
Strains Settling
La-14 starts colonising the intestinal wall. Bl-04 and Lpc-37 begin modulating the immune environment. FOS prebiotics are actively feeding the establishing colonies.
Week 3
Comfort Improving
Gas and post-meal discomfort ease as La-14 and Bl-04 reduce gas-producing bacteria and intestinal inflammation. Most people notice a meaningful shift around week two.
Week 4
Barrier Strengthening
Lp-115 begins reinforcing tight junction proteins in the gut lining. Intestinal permeability starts to reduce — the gut becomes a better filter and less of a source of systemic inflammation.
Week 6
Flora Diversifying
All four strains are now well-established and occupying complementary roles. Short-chain fatty acid production rises, nourishing the colonic epithelium and supporting a more balanced internal environment.
Week 8
Immune Uplift
The gut-immune axis strengthens noticeably. Bl-04's clinical immune benefits come online — fewer minor illnesses, faster recovery, and a more regulated response to allergens and pathogens.
Week 12+
Microbiome Established
A stable, diverse microbiome is maintained by all four strains working in concert. The gut barrier, immune resilience and strain diversity all continue to compound with daily use.
The Formula
Why Our Probiotic
Most probiotics fail before they do anything — stomach acid kills unprotected bacteria before they reach the intestine. MAKTREK® Bi-Pass Technology physically protects each capsule through the stomach, ensuring the full 40 Billion CFU arrives intact. Four strains then work in complementary roles: La-14 colonises the intestinal wall, Bl-04 supports immune defence, Lp-115 reinforces gut barrier integrity, and Lpc-37 modulates inflammation. Marine polysaccharide and FOS prebiotics support colonisation once delivered.
The Science
Evidence-Based Formulation
Every ingredient in our Probiotic is selected based on peer-reviewed clinical research — each strain chosen for a specific, documented role, delivered at a dose that matters, by a system proven to get them there.
01
Multi-Strain vs Single-Strain Probiotics: Systematic Review of Efficacy and Strain Specificity
A systematic review comparing single-strain versus multi-strain probiotic preparations found that multi-strain combinations demonstrate advantages for a broader range of health outcomes, with strain-specific and condition-specific efficacy observed across gastrointestinal, immune, and metabolic endpoints. The evidence supports selecting diverse, clinically validated strains rather than high-dose single-strain approaches for comprehensive probiotic benefit.
↑ broad outcomes
PubMed · European Journal of Clinical Nutrition · 2020
View study
02
Bifidobacterium Lactis Bl-04 Reduces Upper Respiratory Illness Risk in Healthy Adults
A randomised, double-blind, placebo-controlled trial of 465 physically active healthy adults found that supplementation with Bifidobacterium animalis subsp. lactis Bl-04 reduced the risk of upper respiratory illness by 27% compared to placebo over a 150-day winter period (p=0.037). Bl-04 recipients also showed a significantly longer time to first illness and fewer sick days overall. This remains one of the most robustly evidenced probiotic strains for immune defence against respiratory infection.
↓ illness risk
PLOS ONE · West et al. · 2014
View study
03
Lactobacillus Acidophilus Modulates Gut Microbiota and Improves Digestive Comfort
A randomised placebo-controlled trial of Lactobacillus acidophilus supplementation in healthy adults demonstrated significant modulation of intestinal microbiota composition after 8 weeks, with measurable increases in beneficial Lactobacillus populations and reductions in potentially pathogenic species. Participants also reported improvements in bowel regularity, reduced bloating frequency, and improved overall digestive comfort compared to the placebo group, with no reported adverse effects.
↑ digestion
PubMed · Nutrients · 2016
View study
04
Lactobacillus Plantarum Reinforces Intestinal Barrier Integrity and Reduces Gut Permeability
A clinical investigation of Lactobacillus plantarum effects on intestinal barrier function found that supplementation significantly increased expression of key tight junction proteins — including occludin and ZO-1 — compared to control, reinforcing the intestinal epithelial barrier. Participants showed measurable reductions in intestinal permeability markers after 12 weeks, supporting a role for L. plantarum in reducing leaky gut and the associated systemic inflammatory burden.
↑ gut barrier
PubMed · Gut · 2016
View study
05
Lactobacillus Paracasei Reduces Allergic Symptoms and Modulates Th1/Th2 Immune Balance
A randomised controlled trial of Lactobacillus paracasei supplementation in adults with seasonal allergic rhinitis found significant reductions in symptom severity scores, nasal congestion, and IgE-mediated immune responses compared to placebo. L. paracasei modulates the Th1/Th2 immune balance, reducing the disproportionate Th2 response that drives allergic and inflammatory reactions, and supporting a more regulated systemic immune profile with sustained use.
↓ allergy symptoms
PubMed · Allergy · 2014
View study
06
Fructooligosaccharide Prebiotic Selectively Increases Bifidobacterium Populations in the Human Colon
A double-blind, crossover study of fructooligosaccharide supplementation in healthy adults demonstrated selective stimulation of Bifidobacterium species in the colon, with populations increasing significantly versus baseline after 15 days of supplementation. FOS fermentation by colonic bacteria also produced elevated short-chain fatty acid concentrations, particularly butyrate, which nourishes the colonic epithelium and supports gut barrier integrity alongside the probiotic strains it feeds.
↑ Bifidobacterium
PubMed · Gastroenterology · 1995
View study
6 peer-reviewed studies · double-blind, placebo-controlled RCTs
Every claim on this page links to its source
The Formula
What's Inside
01
800mg per serving
Probiotic Blend
4-Strain Probiotic · MAKTREK® Bi-Pass Technology02
Complex Marine Polysaccharide
MAKTREK® Delivery MatrixMAKTREK® delivery matrix that shields live cultures through stomach acid.
03
FOS
Fructooligosaccharide
Prebiotic FibreSelectively feeds Bifidobacterium and Lactobacillus to support colonisation and gut health.
Click label to view full sizeIngredients: Proprietary Blend of Probiotic Bacteria (800mg, 40 Billion CFU): MAKTREK® (Bi-Pass Technology), Lactobacillus Acidophilus (La-14), Bifidobacterium Lactis (Bl-04), Lactobacillus Plantarum (Lp-115), Lactobacillus Paracasei (Lpc-37); Complex Marine Polysaccharide (60mg), Fructooligosaccharide (24mg).
Other Ingredients: Hypromellose (vegetable capsule), Rice Maltodextrin, L-Leucine.
Manufacturer Country: USA
Product Amount: 60 capsules
Warning: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Usage
How to Take It
01
2 Capsules Daily With Food
Take 2 capsules with breakfast or a meal. Food triggers digestive movement that helps the MAKTREK® matrix pass through the stomach at the optimal rate, protecting the live cultures until they reach the intestine.
02
Be Consistent for 4 Weeks Minimum
The gut microbiome shifts gradually. Most people notice meaningful improvement in digestion and comfort between weeks 3 and 6. Stay consistent past the first two weeks before judging — the compound effect is real but takes time.
03
Avoid Hot Drinks at the Same Time
Take at least 20 minutes away from very hot beverages. Extreme heat can affect live cultures before they are protected by the MAKTREK® matrix. Cool or room-temperature water is ideal.
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Suitable for daily long-term use. If pregnant, nursing, or taking prescription medication — particularly antibiotics — consult your physician before use.
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Real Results Take Consistent Use
The microbiome shifts gradually, not overnight. Give your gut the weeks it needs — the benefits compound over time. Consistency is what separates results from wasted money.
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Verified Customer Reviews
What our customers say.
4.8
16 verified reviews
I've tried five or six different probiotics over the years. This is the first where I noticed a clear change in digestion within two weeks. Less bloating, better regularity — the four-strain formula seems to be doing something my previous single-strain products never did.
Started this after a 10-day course of antibiotics. In previous recoveries it took two months to get back to normal. This time it was three weeks. The combination of four strains plus the prebiotic FOS clearly helps the bacteria establish faster.
Good product. Takes a solid 3–4 weeks before the regularity benefit kicks in — don't expect overnight results. But once it does settle, the improvement is consistent and noticeable. Stick with it past the first two weeks.
The B. Lactis Bl-04 strain was the deciding factor for me — it's the only probiotic strain with solid RCT evidence for reducing respiratory illness. Two winters without my usual run of colds. Can't attribute that to one thing, but this is in the mix.
IBS has been an issue for years. Two months on this and the flare-up frequency has reduced significantly. Not a cure, but the gut comfort improvement is real and meaningful. The multi-strain approach makes a difference.
Bought for gut comfort and the bloating reduction alone would justify it. But I've also been noticeably less prone to picking up bugs this winter — the gut-immune connection is clearly real and this formula supports it.
The only thing I'd change is a single-capsule option for travel. But the formula itself is excellent — four properly studied strains, FOS prebiotic, and a delivery system that actually gets them where they need to go.
Most probiotics I've tried haven't done much because unprotected bacteria simply don't survive stomach acid. The MAKTREK® marine polysaccharide protection is the key differentiator here. Six weeks in and my gut health has genuinely improved.
Showing 9 of 16 reviews