The berberine and Lean+ combination is the most effective weight management approach I've tried. Blood sugar is stable, appetite is managed, and I'm down 10 lbs in six weeks without fighting cravings constantly.
Metabolic Fat Loss · Berberine & Lean +
Lean stack
Lean stack
$56.79Subscribe & Save
Sale price
$56.79Subscribe & Save
Regular price
$89.98
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$56.79Subscribe & Save
Sale price
$56.79Subscribe & Save
Regular price
$89.98
10,000+
Already feeling it
4.9 / 5
Star Rating
FDA
Approved Facility
Zero
Fillers Added
Clinically
Dosed Formula
↑25%
Fat oxidation
L-Carnitine · 12-week RCT
↓45%
Insulin resistance
Berberine · 12-week study
↓5lb
Weight loss · 12 weeks
Berberine · 12-week RCT
The Lean Stack combines two of our most targeted weight management formulas — Berberine and Lean + — engineered to work together at every stage of your fat loss journey.
While most supplements target one mechanism, the Lean Stack attacks the problem from two directions: metabolic regulation and active fat burning. The result is a more complete, science-backed approach to sustainable weight management.
Berberine works at the foundation — activating AMPK, the body's metabolic master switch, to regulate blood sugar, reduce fat storage, and improve how efficiently your body processes glucose. By addressing the root metabolic drivers of weight gain, it creates the internal conditions your body needs to lose fat and keep it off.
Lean + builds on that foundation — delivering our Proprietary Active-8 & African Mango Complex alongside L-Carnitine, L-Arginine, Rhodiola Rosea, and Maca Root to accelerate fat metabolism, reduce cravings, and sustain the energy needed to stay consistent and on track.
Together, they support improved metabolic rate, healthier blood sugar levels, reduced appetite, and enhanced fat-burning capacity — a comprehensive daily protocol for people serious about their body composition.
The Lean Stack is designed for daily use alongside a structured diet and training routine, for those who want results that last.
The Science
Evidence-Based Formulation
The Lean Stack pairs two clinically researched mechanisms in a single daily protocol. Berberine activates AMPK — the body's metabolic master switch — to regulate blood sugar, reduce fat storage, and improve insulin sensitivity at the cellular level. Lean + builds on this foundation with African Mango's adipokine research, L-Carnitine's fat transport mechanism, and adaptogenic herbs that reduce the cortisol-driven fat accumulation that undermines most weight loss efforts. Together they address the root metabolic and hormonal drivers of fat gain that single supplements can't reach.
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Berberine Activates AMPK — The Master Metabolic Regulator — in Insulin-Resistant States
“Mechanistic research confirmed berberine activates AMP-activated protein kinase (AMPK) in skeletal muscle and liver cells, improving glucose uptake independent of insulin signalling. AMPK increases GLUT4 glucose transporter translocation to the cell surface, enhancing glucose absorption without requiring additional insulin — directly reducing the fat storage signalling that excess blood glucose triggers.”
View study -
Berberine Reduces Body Weight, BMI, and Abdominal Fat in Randomised Controlled Trial
“A randomised controlled study found berberine produced significant reductions in body weight, BMI, waist circumference, and abdominal fat over 12 weeks. Weight effects operate through AMPK-mediated inhibition of adipogenesis, increased hepatic fatty acid oxidation, and improved insulin signalling that reduces fat storage.”
View study -
Irvingia gabonensis Improves Leptin Sensitivity and Adiponectin — Key Hormones Controlling Appetite and Fat Storage
“African Mango extract significantly improves leptin sensitivity and adiponectin levels in clinical trials. Leptin governs appetite and satiety; adiponectin controls fat metabolism and insulin sensitivity. When these hormones are dysregulated, appetite and fat storage are compromised. Restoring their signalling supports healthy body weight and composition.”
View study -
L-Carnitine Increases Whole-Body Fat Oxidation by 25% and Reduces Body Fat Percentage
“L-Carnitine transports long-chain fatty acids into mitochondria for energy production — without it, fat cannot be burned for fuel. A 12-week RCT demonstrated a 25% increase in whole-body fat oxidation during exercise and significant reductions in body fat percentage. Plasma carnitine levels correlated directly with the degree of fat oxidation improvement.”
View study -
Rhodiola Rosea Reduces Stress-Induced Fatigue by 35% and Normalises Cortisol — a Key Driver of Abdominal Fat
“A double-blind RCT found Rhodiola rosea extract reduced stress-induced fatigue scores by 35% over 12 weeks. The adaptogenic mechanism involves normalising cortisol — elevated levels directly drive abdominal fat storage and disrupt appetite signalling. Physical endurance and mental performance both improved significantly versus placebo.”
View study -
Berberine Matches Metformin for Blood Sugar and HbA1c Reduction — With Superior Lipid Outcomes
“A randomised controlled trial comparing berberine to metformin found berberine reduced HbA1c by 2.0% and fasting blood glucose by 6.9 mmol/L — outcomes equivalent to metformin. Berberine also produced superior lipid improvements, reducing triglycerides by 35.9% and LDL by 21.0% — benefits directly relevant to metabolic fat loss.”
View study
Benefits
- Activates AMPK — the body's master metabolic switch for fat and glucose regulation
- Transports fatty acids into mitochondria for direct fat oxidation via L-Carnitine
- Regulates blood sugar to reduce fat storage signalling after meals
- Improves leptin sensitivity to control appetite and reduce cravings
- Normalises cortisol to reduce stress-driven abdominal fat accumulation
- Supports sustained energy throughout your weight loss journey
Why our Lean stack
Most weight management supplements target one mechanism — appetite, or fat burning, or blood sugar. The Lean Stack addresses all three simultaneously. Berberine operates at the metabolic root: activating AMPK to regulate how the body processes glucose and stores fat, with clinical outcomes that match pharmaceutical intervention. Lean + builds the active layer: African Mango corrects the hormonal signals (leptin, adiponectin) that drive appetite and fat storage, L-Carnitine opens the door for fat to reach the mitochondria and actually be burned, and Rhodiola normalises cortisol — the stress hormone directly responsible for abdominal fat that is typically ignored by fat burner formulas. A capsule and a dropper, two mechanisms working together.
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Description
The Lean Stack combines two of our most targeted weight management formulas — Berberine and Lean + — engineered to work together at every stage of your fat loss journey.
While most supplements target one mechanism, the Lean Stack attacks the problem from two directions: metabolic regulation and active fat burning. The result is a more complete, science-backed approach to sustainable weight management.
Berberine works at the foundation — activating AMPK, the body's metabolic master switch, to regulate blood sugar, reduce fat storage, and improve how efficiently your body processes glucose. By addressing the root metabolic drivers of weight gain, it creates the internal conditions your body needs to lose fat and keep it off.
Lean + builds on that foundation — delivering our Proprietary Active-8 & African Mango Complex alongside L-Carnitine, L-Arginine, Rhodiola Rosea, and Maca Root to accelerate fat metabolism, reduce cravings, and sustain the energy needed to stay consistent and on track.
Together, they support improved metabolic rate, healthier blood sugar levels, reduced appetite, and enhanced fat-burning capacity — a comprehensive daily protocol for people serious about their body composition.
The Lean Stack is designed for daily use alongside a structured diet and training routine, for those who want results that last.
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What's Included
Berberine
Granular Berberine Hydrochloride Extract 8% (bark/root) 790mg, Granular Berberine Hydrochloride Extract 97% (bark) 10mg. Other Ingredients: Cellulose (vegetable capsule), MCC (microcrystalline cellulose), L-Leucine, Olive Oil. 60 capsules.Lean +
Active-8 & African Mango Complex 200mg per serving (1ml): African Mango (Irvingia Gabonensis) Fruit Extract, Maca (Lepidium Meyenii) Root Extract, Astragalus Membranaceus Root Extract, Rhodiola Rosea Root Extract, Pygeum Africanum Root Extract, L-Arginine Base, L-Glutamine, L-Ornithine HCl, L-Carnitine. Other Ingredients: Deionized Water, Ethanol, Organic Citrus Extract, Stevia Extract, Xylitol. 30ml liquid (30 servings).*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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How to Take
Berberine: Take 2 capsules once daily with a meal. For sustained blood sugar coverage, split the dose — 1 capsule with breakfast and 1 capsule with dinner. If you are new to berberine, begin with 1 capsule daily for the first week before increasing to the full dose.
Lean +: Take 1ml (one full dropper) daily in the morning on an empty stomach or 30 minutes before exercise. Hold under your tongue for 30–60 seconds before swallowing for faster absorption. Can be added to a small amount of water if preferred. Shake well before each use.
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Shipping
All orders are dispatched within 1 business day and arrive in 2–4 business days via express shipping.
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One-time orders are charged a flat express shipping rate at checkout.
The Experience
What you'll feel
- Reduced appetite and fewer cravings
- Stable energy between meals
- Improved fat burning during exercise
- Less stress-related fat storage
- Consistent, measurable body composition progress
Your routine
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Verified Customer Reviews
What our customers say.
Based on 39 verified reviews
Bought the Lean Stack? We send every customer an email 3 weeks after delivery where they can leave a review.
I split the berberine between breakfast and dinner and take the Lean+ dropper in the morning. The protocol works — blood sugar is steady all day and the appetite control through the afternoon is the biggest win.
No jitters, no rebound hunger, just consistent progress over eight weeks. The berberine handles the metabolic side and the Lean+ reduces the cravings. Together it's a sustainable stack, not a quick fix.
Good combination. I'll say the results took closer to four weeks to really show rather than two. Once they arrived though — appetite clearly under control, energy better, weight moving steadily. Worth sticking with it.
The Rhodiola in Lean+ addresses the cortisol side of weight gain that most fat burners ignore. I carry stress weight around the middle and this is the first thing that's actually shifted it.
The synergy between these two products is the whole point of buying the stack. Berberine alone is good. Lean+ alone is good. Together the metabolic and appetite effects are meaningfully amplified.
Down 14 lbs in eight weeks alongside light exercise. Energy is the best it's been in years and I'm not fighting hunger between meals. The AMPK activation from berberine combined with the liquid drops is the right approach.
Showing 7 of 39 reviews