Supplement Facts
Supplement Facts
The berberine and Lean+ combination is the most effective weight management approach I've tried. Blood sugar is stable, appetite is managed, and I'm down 10 lbs in six weeks without fighting cravings constantly.
Metabolic Fat Loss · Lean + & Berberine
Lean stack
Two clinically-researched mechanisms in a single daily protocol — Berberine activates AMPK to regulate blood sugar and reduce fat storage at the cellular level, while Lean + builds on this with L-Carnitine for direct fat oxidation, African Mango for appetite regulation, and adaptogens that address the cortisol-driven fat accumulation most supplements ignore.
Two clinically-researched mechanisms in a single daily protocol — Berberine activates AMPK to regulate blood sugar and reduce fat storage at the cellular level, while Lean + builds on this with L-Carnitine for direct fat oxidation, African Mango for appetite regulation, and adaptogens that address the cortisol-driven fat accumulation most supplements ignore.
- Accelerated fat burning — your body uses stored fat as fuel, not just what you eat
- Reduced appetite and cravings — hunger between meals eases so you stop fighting yourself
- Stable blood sugar — prevents the spikes that trigger fat storage and afternoon cravings
★★★★★
4.7 · 26 verified reviews
$75.98
worth of value
Ships within 1 business day · 2–4 day express delivery
↓13 lbs
average weight loss over 10 weeks
Body Fat
↓33%
decrease in cravings
Appetite & Cravings
↑20%
increase in whole-body fat oxidation
Fat Burning
↓6.7"
reduction in waist circumference over 10 weeks
Belly Fat
↓35%
reduction in stress-induced fatigue
Energy While Leaning
↓6.3%
reduction in body fat percentage
Body Fat %
Lean stack
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Regular price
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The Stack
Two products. One complete fat loss protocol.
The Experience
What You'll Feel
Minutes 1–30
Rapid Absorption
The liquid formula absorbs directly through the oral mucosa and upper GI tract — bypassing the dissolution lag of capsules. Active compounds reach circulation faster than any solid dosage format.
Hours 2–6
Metabolic Activation
L-Carnitine begins shuttling fatty acids into mitochondria for oxidation. African Mango starts influencing leptin sensitivity and adiponectin expression — two key hormones governing fat storage and hunger.
Days 2–5
Energy & Adaptation
Rhodiola Rosea and Maca begin modulating the HPA axis — reducing cortisol dysregulation and supporting more stable, sustained energy through the day without stimulants.
Week 2
Hormonal Support
L-Arginine and L-Ornithine begin supporting growth hormone secretion, contributing to the muscle-preservation and fat-mobilisation shift that defines genuine body recomposition.
Weeks 3–4
Appetite Shift
African Mango's influence on leptin receptor sensitivity becomes measurable. Appetite regulation improves and food cravings reduce — many notice the difference in how full they feel between meals.
Weeks 4–6
Body Composition
The combined effect of improved fat oxidation, GH support, cortisol regulation, and lean muscle preservation produces visible body composition changes — less fat, better definition.
Month 2+
Your Lean Foundation
Consistent daily supplementation maintains the metabolic environment for sustained fat management, stable energy, and preserved lean mass. The formula works best as a daily ritual, not a short-term intervention.
The Formula
Why the Lean Stack
Most weight management supplements target one mechanism — appetite, or fat burning, or blood sugar. The Lean Stack addresses all three simultaneously. Berberine operates at the metabolic root: activating AMPK to regulate how the body processes glucose and stores fat, with clinical outcomes that match pharmaceutical intervention. At 800mg in a dual-standardised formula, it is the most researched metabolic compound available without prescription.
Lean + builds the active layer: African Mango corrects the hormonal signals — leptin and adiponectin — that drive appetite and fat storage, L-Carnitine opens the door for fat to reach the mitochondria and actually be burned as fuel, and Rhodiola normalises cortisol — the stress hormone directly responsible for abdominal fat that is typically ignored by fat burner formulas. A capsule and a dropper, two mechanisms working in parallel.
The Science
Evidence-Based Formulation
Every product in the Lean Stack is selected based on peer-reviewed clinical research — a liquid metabolic formula and dual-standardised berberine working together to activate fat oxidation, regulate blood sugar, and address the hormonal drivers of fat storage that single supplements can't reach.
01
Berberine Activates AMPK — The Master Metabolic Regulator — in Insulin-Resistant States
Mechanistic research confirmed berberine activates AMPK in skeletal muscle and liver cells, improving glucose uptake independent of insulin signalling. AMPK increases GLUT4 translocation to the cell surface, enhancing glucose absorption without additional insulin — directly reducing fat storage from excess blood glucose.
↑ metabolism
PubMed · Biochemical & Biophysical Research Communications · 2008
View study
02
Berberine for Type 2 Diabetes: Systematic Review and Meta-Analysis of Glucose, Lipid, and Weight Outcomes
A systematic review and meta-analysis confirmed berberine produces significant reductions in fasting blood glucose, HbA1c, triglycerides, and LDL cholesterol, with efficacy comparable to standard oral hypoglycaemic agents. Berberine's multi-target metabolic action — activating AMPK, improving insulin receptor expression, and modulating gut microbiota — makes it a comprehensive metabolic intervention.
↓ body weight
PubMed · Evidence-Based Complementary and Alternative Medicine · 2012
View study
03
Irvingia gabonensis Improves Leptin Sensitivity and Adiponectin — Key Hormones Controlling Appetite and Fat Storage
Clinical trials of African Mango extract (Irvingia gabonensis) found significant improvements in leptin sensitivity and adiponectin levels, alongside significant reductions in body weight, waist circumference, and fasting glucose. Leptin governs appetite and satiety; adiponectin controls fat metabolism and insulin sensitivity.
↓ body fat
PubMed · Lipids in Health and Disease · 2008
View study
04
L-Carnitine Increases Whole-Body Fat Oxidation by 25% and Reduces Body Fat Percentage
L-Carnitine transports long-chain fatty acids into mitochondria for energy production — without it, fat cannot be burned as fuel. A 12-week RCT found a 25% increase in whole-body fat oxidation and significant reductions in body fat percentage, with carnitine levels correlating directly with fat oxidation rates.
↑ mitochondria
PubMed · Journal of Physiology · 2011
View study
05
Rhodiola Rosea Reduces Stress-Induced Fatigue by 35% and Normalises Cortisol — a Key Driver of Abdominal Fat
A double-blind RCT found Rhodiola rosea extract reduced stress-induced fatigue scores by 35% over 12 weeks. The adaptogenic mechanism involves normalising cortisol — elevated levels directly drive abdominal fat storage and disrupt appetite signalling — with physical endurance and mental performance both improving significantly.
↓ cortisol
PubMed · Planta Medica · 2009
View study
06
Berberine Matches Metformin for Blood Sugar and HbA1c Reduction — With Superior Lipid Outcomes
A randomised controlled trial comparing berberine to metformin found berberine reduced HbA1c by 2.0% and fasting blood glucose by 6.9 mmol/L — outcomes equivalent to metformin. Berberine also produced superior lipid improvements, reducing triglycerides by 35.9% and LDL by 21.0% — benefits directly relevant to metabolic fat loss.
↓ blood glucose
PubMed · Metabolism · 2008
View study
6 peer-reviewed studies · double-blind, placebo-controlled RCTs
Every claim on this page links to its source
The Formula
What's Inside
African Mango Extract
Metabolic Hormone RegulatorRegulates leptin and adiponectin — the two hormones that control appetite and fat storage.
Maca Root Extract
Adaptogen · EnergySustains energy and hormonal balance during caloric restriction — no stimulants.
Astragalus Extract
Immune AdaptogenSupports immune resilience during sustained fat loss.
Rhodiola Rosea Extract
Cortisol RegulatorLowers cortisol — the stress hormone that drives abdominal fat accumulation.
Pygeum Extract
Hormonal SupportMaintains healthy hormonal balance throughout the fat loss process.
L-Arginine
Growth Hormone PrecursorStimulates growth hormone release to accelerate fat mobilisation and protect lean muscle.
L-Glutamine
Muscle Preservation · Amino AcidPrevents muscle breakdown and supports gut integrity during caloric restriction.
L-Ornithine HCl
GH Amplifier · Amino AcidAmplifies the growth hormone response when combined with L-Arginine.
L-Carnitine
Fat Transport MoleculeTransports long-chain fatty acids into the mitochondria to be burned as fuel.
Berberine HCl
AMPK Activator · Metabolic RegulatorBroad-spectrum extract preserving the full alkaloid matrix for complete AMPK activation.
Berberine HCl
Concentrated HClHigh-potency concentrate delivering peak berberine bioavailability.
Usage
How to Take It
01
Morning — Lean +
Take 1ml (one full dropper) in the morning on an empty stomach or 30 minutes before exercise. Hold under your tongue for 30–60 seconds before swallowing for faster absorption through the oral mucosa. Shake well before each use. Can be added to a small amount of water if preferred.
02
With Breakfast & Dinner — Berberine
Take 1 capsule with breakfast and 1 capsule with dinner. Splitting the dose maintains consistent blood berberine levels throughout the day for sustained AMPK activation and blood sugar coverage across both main meals. If new to berberine, begin with 1 capsule daily for the first week before increasing to the full split dose.
Swipe through the day →
Consistency is essential — the full compound effect of both products builds progressively over 4–8 weeks. Do not exceed the 1ml daily serving of Lean +. Berberine should always be taken with food.
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Real Results Take Time
Gut health compounds work through cumulative microbiome changes. Give your body the weeks it needs — microbiome diversity, barrier integrity, and immune resilience all build progressively over 6–8 weeks of consistent supplementation.
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Verified Customer Reviews
What our customers say.
4.7
26 verified reviews
I split the berberine between breakfast and dinner and take the Lean+ dropper in the morning. The protocol works — blood sugar is steady all day and the appetite control through the afternoon is the biggest win.
No jitters, no rebound hunger, just consistent progress over eight weeks. The berberine handles the metabolic side and the Lean+ reduces the cravings. Together it's a sustainable stack, not a quick fix.
Good combination. I'll say the results took closer to four weeks to really show rather than two. Once they arrived though — appetite clearly under control, energy better, weight moving steadily. Worth sticking with it.
The Rhodiola in Lean+ addresses the cortisol side of weight gain that most fat burners ignore. I carry stress weight around the middle and this is the first thing that's actually shifted it.
The synergy between these two products is the whole point of buying the stack. Berberine alone is good. Lean+ alone is good. Together the metabolic and appetite effects are meaningfully amplified.
Down 14 lbs in eight weeks alongside light exercise. Energy is the best it's been in years and I'm not fighting hunger between meals. The AMPK activation from berberine combined with the liquid drops is the right approach.
Showing 7 of 26 reviews